![T-cell activation by anti-CTLA-4 antibodies. Notes: (A) Tumor antigens... | Download Scientific Diagram T-cell activation by anti-CTLA-4 antibodies. Notes: (A) Tumor antigens... | Download Scientific Diagram](https://www.researchgate.net/publication/299401459/figure/fig1/AS:350073809588224@1460475508393/T-cell-activation-by-anti-CTLA-4-antibodies-Notes-A-Tumor-antigens-can-be-presented.png)
T-cell activation by anti-CTLA-4 antibodies. Notes: (A) Tumor antigens... | Download Scientific Diagram
![Anti-CTLA-4 antibodies drive myeloid activation and reprogram the tumor microenvironment through FcγR engagement and type I interferon signaling | Nature Cancer Anti-CTLA-4 antibodies drive myeloid activation and reprogram the tumor microenvironment through FcγR engagement and type I interferon signaling | Nature Cancer](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fs43018-022-00447-1/MediaObjects/43018_2022_447_Fig1_HTML.png)
Anti-CTLA-4 antibodies drive myeloid activation and reprogram the tumor microenvironment through FcγR engagement and type I interferon signaling | Nature Cancer
![Molecules | Free Full-Text | Molecular Interactions of Antibody Drugs Targeting PD-1, PD-L1, and CTLA-4 in Immuno-Oncology | HTML Molecules | Free Full-Text | Molecular Interactions of Antibody Drugs Targeting PD-1, PD-L1, and CTLA-4 in Immuno-Oncology | HTML](https://www.mdpi.com/molecules/molecules-24-01190/article_deploy/html/images/molecules-24-01190-g001-550.jpg)
Molecules | Free Full-Text | Molecular Interactions of Antibody Drugs Targeting PD-1, PD-L1, and CTLA-4 in Immuno-Oncology | HTML
![Inhibitors of immune checkpoints—PD-1, PD-L1, CTLA-4—new opportunities for cancer patients and a new challenge for internists and general practitioners | SpringerLink Inhibitors of immune checkpoints—PD-1, PD-L1, CTLA-4—new opportunities for cancer patients and a new challenge for internists and general practitioners | SpringerLink](https://media.springernature.com/lw685/springer-static/image/art%3A10.1007%2Fs10555-021-09976-0/MediaObjects/10555_2021_9976_Fig2_HTML.png)
Inhibitors of immune checkpoints—PD-1, PD-L1, CTLA-4—new opportunities for cancer patients and a new challenge for internists and general practitioners | SpringerLink
![800 Dual targeting of CTLA-4 and CD47 on Treg cells rejuvenates immunity against solid tumors | Journal for ImmunoTherapy of Cancer 800 Dual targeting of CTLA-4 and CD47 on Treg cells rejuvenates immunity against solid tumors | Journal for ImmunoTherapy of Cancer](https://jitc.bmj.com/content/jitc/9/Suppl_2/A835/F2.large.jpg)
800 Dual targeting of CTLA-4 and CD47 on Treg cells rejuvenates immunity against solid tumors | Journal for ImmunoTherapy of Cancer
![Localized low-dose anti-CTLa4 antibody therapy is efficacious. (A-C)... | Download Scientific Diagram Localized low-dose anti-CTLa4 antibody therapy is efficacious. (A-C)... | Download Scientific Diagram](https://www.researchgate.net/publication/261375485/figure/fig1/AS:616352406597648@1523961273576/Localized-low-dose-anti-CTLa4-antibody-therapy-is-efficacious-A-C-Mice-n-10-11-per.png)
Localized low-dose anti-CTLa4 antibody therapy is efficacious. (A-C)... | Download Scientific Diagram
![800 Dual targeting of CTLA-4 and CD47 on Treg cells rejuvenates immunity against solid tumors | Journal for ImmunoTherapy of Cancer 800 Dual targeting of CTLA-4 and CD47 on Treg cells rejuvenates immunity against solid tumors | Journal for ImmunoTherapy of Cancer](https://jitc.bmj.com/content/jitc/9/Suppl_2/A835/F1.large.jpg)
800 Dual targeting of CTLA-4 and CD47 on Treg cells rejuvenates immunity against solid tumors | Journal for ImmunoTherapy of Cancer
![Uncoupling therapeutic from immunotherapy-related adverse effects for safer and effective anti-CTLA-4 antibodies in CTLA4 humanized mice | Cell Research Uncoupling therapeutic from immunotherapy-related adverse effects for safer and effective anti-CTLA-4 antibodies in CTLA4 humanized mice | Cell Research](https://media.springernature.com/m685/springer-static/image/art%3A10.1038%2Fs41422-018-0012-z/MediaObjects/41422_2018_12_Fig1_HTML.png)
Uncoupling therapeutic from immunotherapy-related adverse effects for safer and effective anti-CTLA-4 antibodies in CTLA4 humanized mice | Cell Research
![Frontiers | Beyond T-Cells: Functional Characterization of CTLA-4 Expression in Immune and Non-Immune Cell Types Frontiers | Beyond T-Cells: Functional Characterization of CTLA-4 Expression in Immune and Non-Immune Cell Types](https://www.frontiersin.org/files/Articles/608024/fimmu-11-608024-HTML/image_m/fimmu-11-608024-g001.jpg)
Frontiers | Beyond T-Cells: Functional Characterization of CTLA-4 Expression in Immune and Non-Immune Cell Types
![Differential control of human Treg and effector T cells in tumor immunity by Fc-engineered anti–CTLA-4 antibody | PNAS Differential control of human Treg and effector T cells in tumor immunity by Fc-engineered anti–CTLA-4 antibody | PNAS](https://www.pnas.org/cms/10.1073/pnas.1812186116/asset/4b8abb3b-e9df-4c40-93c4-46e741c8042f/assets/graphic/pnas.1812186116fig04.jpeg)
Differential control of human Treg and effector T cells in tumor immunity by Fc-engineered anti–CTLA-4 antibody | PNAS
![Anti-CTLA-4 and anti-PD-1 immunotherapies repress tumor progression in preclinical breast and colon model with independent regulatory T cells response - ScienceDirect Anti-CTLA-4 and anti-PD-1 immunotherapies repress tumor progression in preclinical breast and colon model with independent regulatory T cells response - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S1936523322000675-gr1.jpg)
Anti-CTLA-4 and anti-PD-1 immunotherapies repress tumor progression in preclinical breast and colon model with independent regulatory T cells response - ScienceDirect
![Frontiers | Anti-PD-1 and Anti-CTLA-4 Therapies in Cancer: Mechanisms of Action, Efficacy, and Limitations Frontiers | Anti-PD-1 and Anti-CTLA-4 Therapies in Cancer: Mechanisms of Action, Efficacy, and Limitations](https://www.frontiersin.org/files/Articles/330851/fonc-08-00086-HTML/image_m/fonc-08-00086-g001.jpg)
Frontiers | Anti-PD-1 and Anti-CTLA-4 Therapies in Cancer: Mechanisms of Action, Efficacy, and Limitations
![John Libbey Eurotext - Journal de Pharmacie Clinique - PK/PD relationships of therapeutic monoclonal antibodies used in oncology John Libbey Eurotext - Journal de Pharmacie Clinique - PK/PD relationships of therapeutic monoclonal antibodies used in oncology](https://www.jle.com/e-docs/00/04/CF/5F/jlejpc0418gr2.jpg)
John Libbey Eurotext - Journal de Pharmacie Clinique - PK/PD relationships of therapeutic monoclonal antibodies used in oncology
![Inhibitors of immune checkpoints—PD-1, PD-L1, CTLA-4—new opportunities for cancer patients and a new challenge for internists and general practitioners | SpringerLink Inhibitors of immune checkpoints—PD-1, PD-L1, CTLA-4—new opportunities for cancer patients and a new challenge for internists and general practitioners | SpringerLink](https://media.springernature.com/lw685/springer-static/image/art%3A10.1007%2Fs10555-021-09976-0/MediaObjects/10555_2021_9976_Fig3_HTML.png)
Inhibitors of immune checkpoints—PD-1, PD-L1, CTLA-4—new opportunities for cancer patients and a new challenge for internists and general practitioners | SpringerLink
![Schematic representation of CTLA-4 and anti-CTLA-4 mechanisms of action... | Download Scientific Diagram Schematic representation of CTLA-4 and anti-CTLA-4 mechanisms of action... | Download Scientific Diagram](https://www.researchgate.net/publication/342750704/figure/fig2/AS:910719696531456@1594143904031/Schematic-representation-of-CTLA-4-and-anti-CTLA-4-mechanisms-of-action-on-T-cell.png)